It is known that, in bacteria, genes are expressed as a response to metabolic or any external stress in order to increase their chance of survival. One such gene in E.coli is the rpoS gene; it regulates the expression of a wide variety of stress-related genes which triggers entrance into stationary phase. We use a genetically engineered rpoS mutant to study the interaction of two competing species of bacteria. | ![]() Microfabricated environments are used to study the evolutionary dynamics of bacteria when subjected to metabolic or physical stress |
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